The authors determined the efficiency of the coagulant-flocculant compositions, which depend on the conditions of reagent introduction, special qualities of wastewater, nature of the coagulant, concentration, molecular weight and charge. The paper explores the issue of optimizing the removal of protein and lipid impurities from wastewater under exposure to the compositions of coagulants and flocculants; in this case anionic acrylamide/sodium acrylate copolymers were analyzed. It has been established that by adding compositions of coagulants with flocculants to wastewater it is possible to significantly reduce the content of protein and lipid impurities.